2010 Journal Articles Acknowledging FSMA Funding

Through December 14, 2010, FSMA is proud to have contributed funding to the research published in the following 17 journal articles.

1. The Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP INTEND): test development and reliability.
Glanzman AM, Mazzone E, Main M, Pelliccioni M, Wood J, Swoboda KJ, Scott C, Pane M, Messina S, Bertini E, Mercuri E, Finkel RS. Neuromuscular Disorders.
FSMA funding to University of Pennsylvania, University of Utah, and CBS Squared.

2. Embryonic stem cell-derived neural stem cells improve spinal muscular atrophy phenotype in mice.
Corti S, Nizzardo M, Nardini M, Donadoni C, Salani S, Ronchi D, Simone C, Falcone M, Papadimitriou D, Locatelli F, Mezzina N, Gianni F, Bresolin N, Comi GP.  Brain.
FSMA funding to the University of Milan.

3. SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy.
Riessland M, Ackermann B, Förster A, Jakubik M, Hauke J, Garbes L, Fritzsche I, Mende Y, Blumcke I, Hahnen E, Wirth B.  Human Molecular Genetics.
FSMA funding to University of Cologne.

4. Identification of novel interacting protein partners of SMN using tandem affinity purification.
Shafey D, Boyer JG, Bhanot K, Kothary R.    Journal of Proteome Research.
FSMA funding to the University of Ottawa.

5. High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function.
Fallini C, Bassell GJ, Rossoll W.     Molecular Neurodegeneration.
FSMA funding to Emory University.

6. A model of motor neuron loss: selective deficits after ricin injection.
Coutts M, Kong LX, Keirstead HS.    PloS One.
FSMA funding to University of California, Irvine.

7.  Compound muscle action potential and motor function in children with spinal muscular atrophy.
Lewelt A, Krosschell KJ, Scott C, Sakonju A, Kissel JT, Crawford TO, Acsadi G, D'anjou G, Elsheikh B, Reyna SP, Schroth MK, Maczulski JA, Stoddard GJ, Elovic E, Swoboda KJ.      Muscle and Nerve.
FSMA funding to the Project Cure SMA Clinical Trial Network.

8. Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice.
Heier CR, Satta R, Lutz C, DiDonato CJ.    Human Molecular Genetics.
FSMA funding to Northwestern University.

9. SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy.
Swoboda KJ, Scott CB, Crawford TO, Simard LR, Reyna SP, Krosschell KJ, Acsadi G, Elsheik B, Schroth MK, D'Anjou G, LaSalle B, Prior TW, Sorenson SL, Maczulski JA, Bromberg MB, Chan GM, Kissel JT; Project Cure Spinal Muscular Atrophy Investigators Network.    PLoS One.
FSMA funding to the Project Cure SMA Clinical Trial Network.

10. A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2.
Jodelka FM, Ebert AD, Duelli DM, Hastings ML.    Human Molecular Genetics.
FSMA funding to Rosalind Franklin University.

11. Development of electrocardiogram intervals during growth of FVB/N neonate mice.
Heier CR, Hampton TG, Wang D, Didonato CJ.    BMC Physiology.
FSMA funding to Northwestern University.

 12, Conserved Genes Act as Modifiers of Invertebrate SMN Loss of Function Defects.
Dimitriadi M, Sleigh JN, Walker A, Chang HC, Sen A, Kalloo G, Harris J, Barsby T, Walsh MB, Satterlee JS, Li C, Van Vactor D, Artavanis-Tsakonas S, Hart AC.    PLoS Genetics.
FSMA funding to Harvard University.

13.  Alpha-Synuclein Loss in Spinal Muscular Atrophy. 
Acsadi G, Li X, Murphy KJ, Swoboda KJ, Parker GC. Journal of Molecular Neuroscience.
FSMA funding to the University of Utah.

14. Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord.
Rossi SL, Nistor G, Wyatt T, Yin HZ, Poole AJ, Weiss JH, Gardener MJ, Dijkstra S, Fischer DF, Keirstead HS.  PLoS One.
FSMA funding to the University of California, Irvine.

15. Human motor neuron generation from embryonic stem cells and induced pluripotent stem cells.
Nizzardo M, Simone C, Falcone M, Locatelli F, Riboldi G, Comi GP, Corti S.    Cell and Molecular Life Sciences.
FSMA funding to the University of Milan.

16.  A novel Caenorhabditis elegans allele smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds.
Sleigh JN, Buckingham SD, Esmaeili B, Viswanathan M, Cuppen E, Westlund BM, Sattelle DB.  Human Molecular Genetics.
FSMA funding to Cambria Biosciences.

17. Antisense oligonucleotides and spinal muscular atrophy: skipping along.
Burghes AH, McGovern VL.  Genes and Development.
FSMA funding to The Ohio State University.